3D bioprinting combined with organoids is revolutionizing drug discovery by creating, precise, patient-specific 3D tissue models that better mimic human physiology than 2D cultures or animal models. These technologies allow for accelerated high-throughput screening of drug efficacy, safety, and toxicity, reducing reliance on animal testing.
3D Bioprinted Liver Tissue with Vascular System as an Innovative Model for Drug Toxicity and Anticancer Therapy Efficacy Assessment
The aim of the project is to develop innovative bioinks dedicated to the bioprinting of a 3D model of bionic liver tissue, both healthy and cancerous, with a vascular system intended for:
Toxicological tests
Research on the efficacy of new drug candidates
The idea of creating a 3D model for pharmacological research addresses the significant limitations of currently used preclinical research models, both at the in vitro and in vivo stages. The models developed within the project will enable faster and more precise testing of new active substances. They will particularly expedite the assessment of their toxicity and the selection of active substance concentrations.
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